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2 edition of Heat transfer and mixing studies in a mechanically agitated pilot-scale bioreactor found in the catalog.

Heat transfer and mixing studies in a mechanically agitated pilot-scale bioreactor

Pankaj Mohan

Heat transfer and mixing studies in a mechanically agitated pilot-scale bioreactor

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  • 29 Currently reading

Published by University of Birmingham in Birmingham .
Written in English


Edition Notes

Thesis (Ph.D) - University of Birmingham, School of Chemical Engineering.

Statementby Pankaj Mohan.
ID Numbers
Open LibraryOL20916043M

Design of Municipal Wastewater Treatment Plants pattern has a negative effect on oxygen transfer efficiency. Pham et al. () reported that a 2-m deep tank (with a length-to-width ratio equal to 1) produced , , and % clean-water oxygen transfer efficiency per meter of water submergence at a m3/hr air-flow rate when containing 0. Ph.D. Engineers (Entry Level) – Bioprocess Engineers Description: The DuPont Biochemical Sciences and Engineering group within Central Research and Development has an immediate opening for Biochemical Engineers with a strong background in process research and. Principles of Fermentation Technology, 2nd Edn. Some representative values of /Lmax (obtained under the conditions specified in the original reference) for a range of organisms. A perfluorocarbon-based oxygen delivery system to a membrane bioreactor introduced to improve the MGR technology for pilot-scale studies. 8 However, the use of pressurised bioreactor systems to improve DO transfer might not be effective for prolonged production periods because of an increase in free and mycelial attached polysaccharides File Size: 3MB.

A. JOURNAL PUBLICATIONS. No. Authors Title of paper Name of Journal vol., page & year. 1 Joshi, J.B., and Mass Transfer Characteristics of Trans. Instn.


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Heat transfer and mixing studies in a mechanically agitated pilot-scale bioreactor by Pankaj Mohan Download PDF EPUB FB2

Gas holdup, mixing, liquid circulation and gas–liquid oxygen transfer were characterized in a large (∼ m 3) draft-tube airlift bioreactor agitated with Prochem ® hydrofoil impellers placed in the draft-tube.

Measurements were made in water and in cellulose fiber slurries Cited by: In this work the mixing and mass transfer performance of a high power agitated pilot scale bioreactor has been characterised using a novel combination of computational fluid dynamics (CFD) and.

Airlift bioreactors are tower reactors for large-scale aerobic cultures where the mixing of the culture broth is done by the inserted gas via an airlift pump (Fig. ).This pump injects compressed air at the bottom of the discharge pipe, which is immersed in the liquid.

The compressed air mixes with the liquid, causing the gas–liquid mixture to be less dense than the rest of the liquid.

Heat transfer studies in a coiled agitated vessel with varying heat input is presented using two agitators namely propeller and disk turbine. Heat transfer rate increases with agitator speed for.

AirLift (or GasLift) bioreactors are an alternative to mechanically agitated systems that reduce shear stress and heat generation by eliminating the mechanical agitator. Airlift systems are similar to bubble column reactors where oxygen transfer, internal circulation, and mixing are achieved by bubbling air.

erally the mass transfer capability. Liquid mixing can also become important in larger bioreactors (working volume greater t L). The chief determinants of the mass-transfer coefficient (k la) in a mechanically agitated, aerobic bioreactor are the agitator specific power (power/volume, P/V) and the superficial gas velocity (U s), which File Size: KB.

S series Pilot Scale Bioreactors / Fermenters were designed with the intention to face all the problems related to scaling-up, from the laboratory to the production stage, with maximum easiness.

All fermenters/bioreactors of this series are compact and flexible (optionally on wheels) with the possibility to be installed even in limited spaces. Mixing and mass transfer in a pilot scale U-loop bioreactor† Leander A.H. Petersen1,3, John Villadsen2, Sten B.

Jørgensen1, Krist V. Gernaey1* 1. CAPEC-PROCESS Research Centre, Department of Chemical and Biochemical Engineering, Technical University of Denmark, Lyngby, Denmark 2.

Shareable Link. Use the link below to share a full-text version of this article with your friends and colleagues. Learn more. Tubular and the flat plate are the two most common general designs of microalgal photobioreactors.

Desired photobioreactors for microalgal mass production have effective liquid mixing to promote nutrients mixing and gas mass transfer; have adequate surface area for light capture; prevent significant accumulation of oxygen; allow for ease of scale-up; and have low material and Cited by: 1.

Mark Simmons is a Chemical Engineer and Professor of Fluid Mechanics at the University of Birmingham. He has been Head of School since Mark graduated from the University of Nottingham in with a Masters in Chemical Engineering and stayed on to undertake PhD study with Professor Barry Azzopardi in the area of liquid-liquid flows of interest to the oil and gas industry.

Viscosity Viscosity is the most important property affecting flow behaviour of a fluid; viscosity is related to the fluid's resistance to motion. Viscosity has a marked effect on pumping, mixing, mass transfer, heat transfer and aeration of fluids; these in turn exert a. Design of an airlift loop bioreactor and pilot scales studies with fluidic oscillator induced microbubbles for growth of a microalgae Dunaliella salina William B.

Zimmerman 1*, Mohammad Zandi 2, HC Hemaka Bandulasena 1, Václav Tesa ř3, D. James Gilmour 4, Kezhen Ying 1 1Department of Chemical and Biological Engineering, University of Sheffield, Mappin. The Bioreactors – Fermenters of the I series are highly automated fermentation systems, available from liters up to 30 m 3, (, cu.

ft.), fully control system technology permits the linking of several units by ETHERNET, for the eventual connection to the supervision system. PRODUCT | BIOFORS TM PRODUCTS: BIOFORS TM Bioreactor / Fermentor System. SOLUTION BIOFORCE is your your specialist for bioreactor and products are designed and manufactured in Malaysia and marketed under the established brand name of BIOFORS will benefit from high quality and inovative systems, with optimal performance and flexibility which your.

laboratory and pilot scale (7–9). The automated workstation features an integrated liquid handler, which can remove the cap of a single-use vessel to enable initial media load, seeding, sampling, and bolus additions.

Culture or feed medium can be transferred preformulated by the pipetting module, or the system can be used to automatically make upFile Size: 1MB. Khare AS, Niranjan K. Mechanically agitated contactors: gas hold up in highly viscous media. IChemE Res Event Proc ; 1: – Khare AS, Niranjan K.

Impeller-agitated aerobic reactor: the influence of tiny bubbles on gas hold-up and mass transfer in highly viscous liquids. Chem Eng Sci ; – Khare AS, Niranjan K.

For mixing of mechanically sensitive mycelial microorganisms, mixing systems are recommended, which generate dominating axial flows, thereby ensuring a more even mixing throughout the reactor's volume. Ekato Intermig mixing systems are among the most widespread ones. The so-called "Counter-flow mixing system" is known.

Breman BB, Beenackers AACM, Bouma MJ, Van der Werf MH () Axial liquid mixing and a gas—liquid multi-stage agitated contactor (MAC). Chem Eng Res Des – Google Scholar Brotherton JD, Chau PC () Modeling of axial-flow hollow fiber cell culture by:   A pilot scale ( l reactor) of an entrapped mixed microbial cell (EMMC) process was fabricated and tested for simultaneous removal of carbon and nitrogen.

Process performance, operational stability, and maintenance requirements were all determined. Two sources of actual agricultural processing wastewater containing a high concentration of chemical oxygen demand (COD) (about Cited by: 7.

The commercial success of mammalian cell-derived recombinant proteins has fostered an increase in demand for novel single-use bioreactor (SUB) systems that facilitate greater productivity, increased flexibility and reduced costs (Zhang et al., ).These systems exhibit fluid flow regimes unlike those encountered in traditional glass/stainless steel bioreactors because of the way in which Cited by: Flexible, pilot-scale bioreactor: • 80L or L fed-batch bioreactor equivalent depending on disposable size in use • Diagnostic and therapeutic uses • Produce mAbs, recombinant proteins or virus • Culture suspension or adherent cell lines Single-Use: • Supplied sterile and ready to use.

The bioreactors used for various plant cell cultures are classified as mechanically agitated, pneumatically driven, disposable and non-agitated (Fig. Bioreactor studies on the effect of. The project consisted of a side-by-side pilot demonstration of six different membrane bioreactor (MBR) systems at the Honolulu wastewater treatment plant (WWTP) in Ewa Beach, Hawaii, and a variety of activities, including bench- and pilot-scale tests, aeration testing, and a feasibility study.

The start-up of a pilot-scale membrane bioreactor equipped with submerged ultrafiltration membranes to treat municipal wastewater has been studied. Attention has been paid to determine membrane separation effects on biomass development in a reactor operated without inoculation.

Studies on cavern development in mixing a yield stress fluid in a pilot-scale proto-fermenter (English) Studies on cavern development in mixing a yield stress fluid in a pilot-scale proto-fermenter Heat transfer to newtonian fluid in a stirred tank.

A comparative. At ESSENT (formerly VAM) a bioreactor study (Woelders and Oonk, ) was initiated in with the Mechanically Separated Organic Residue (MSOR) of a waste separation plant at the ESSENT treatment facility. As in many other studies, the aim of the work was largely focused on the degradation aspect of MSOR (Oonk and Woelders, ).

In addition to these papers, the interested reader will find reference to studies of evaporative and ebullient heat transfer among the papers included in: change of phase – condensation (JJ), heat transfer applications – heat pipes and heat exchangers (Q), and heat transfer applications – general (S).

pharmtech & ingredients 21st international exhibition of equipment, raw materials and technologies for pharmaceutical production 19 – Automated Bench-Scale Bioreactor Design 3 down the organic waste and nutrients to produce an organic-free liquid. In stage one, replicated wastewater is pumped into the system until the reactor is full.

During stage two, air is pumped through the mix while the. Hosseini S, Petel D, Ein-Mozaffari F, Mehrvar M. Study of solid-liquid mixing in agitated tanks through computational fluid dynamics modeling.

Ind Eng Chem Res ;– Web of Science Crossref Google ScholarCited by: 3. A complete reference for fermentation engineers engaged in commercial chemical and pharmaceutical production, Fermentation and Biochemical Engineering Handbook emphasizes the operation, development and design of manufacturing processes that use fermentation, separation and purification techniques.

Contributing authors from companies such as Merck, Eli Lilly, Amgen and Bristol-Myers. The bioactive compounds of plants have world-wide applications in pharmaceutical, nutraceutical and food industry with a huge market.

In this book, a group of active researchers have addressed on the most recent advances in plant cell and organ cultures for the production of biomass and bioactive compounds using bioreactors.

Chisti, Y., in Kirk-Othmer Encyclopedia of Chemical Technology Online, ISBNWiley, New York, Decemberpp. 1–Mass transfer. Tabatabaei, M. A.K. Rozentsvaig and Ch.S. Strashinskii, Modeling of heat transfer conditions in cooling lubricant emulsions with low-boiling continuous media in narrow gaps, International Journal of Heat and Mass Transfer,(), ().

Medicinal Plant Biotechnology-Teaching Book. Published on May Immobilization Feeding of Precursors Elicitors In-Situ Product Removal Strategies Biotransformation Studies Bioreactor and Scale-Up Studies Biosynthetic Pathway Mapping and Metabolic Engineering Biosynthesis of Podophyllotoxin Biosynthesis.

FOREWORD The formation of the United States Environmental Protection Agency marked a new era of environmental awareness in America. This Agency's goals are national in scope and encompass broad responsibility in the areas of air and water pollution, solid wastes, pesticides, and radiation.

Heat transfer fluids used to date include hot com- bustion gases, hot oil, steam, and molten salts. Offgas from desorption is typically processed (3) to re- move particulates. Volatiles in the offgas may be burned in an afterburner, collected on activated carbon, or recovered in condensation equipment.

For growth kinetics studies of A. annua hairy roots, we harvested root biomass and measured medium pH and conductivity after 6, 14, or 21 days in shake flasks and 1 L mist reactors. The rate of medium delivery was 25 mL min − A. annua the misting cycle variations are shown in Table kinetics of A.

annua in shake flasks with media analyses were previously published (Kim et al Cited by: Utilization of a Microbubble Dispersion to Increase Oxygen Transfer in Pilot-Scale Baker’ s Yeast Fermentation Unit Pramuk Parakulsuksatid (ABSTRACT) In the large-scale production of Saccharomyces cerevisiae (baker’ s yeast), oxygen transfer, which is one of the major limiting factors, is improved by using high agitation rates.

Full text of "Principle of Mass Transfer & Separation Process by B.k Dutta" See other formats. A pilot-scale liquid-solid circulating fluidized bed (LSCFB) bioreactor was employed for biological nutrient removal from municipal wastewater at .38 Fundamentals of Biochemical Engineering of catalase, about 50 percent of the activity was lost when y(J was x • However, Thomas and Dimnill () studied the effect of shear on catalase and urease activities by using a coaxial cylindrical viscometer that was sealed to .